The COVID-19 vaccines have proven instrumental around the globe, raising hopes for an end to the pandemic and a return to normal life. But as the pandemic endures, many countries are experiencing additional waves of infection, and people are struggling to comply and cope with ongoing social restrictions. Additionally, vaccine rollout campaigns are being met with concerns over safety. Scrutiny is high as society is becoming impatient for post-pandemic life, and vaccine manufacturers and regulators push for transparency during the clinical development process.